Pros
Genentech boasts an outstanding scientific community with most scientists rivaling assistant professors in their field. Postdocs are given free reign to explore any aspect of biology as they would in an academic lab, but without the funding restraints of limited NIH budgets. The depth of scientific experience among the ranks of scientists is impressive and drives highly efficient research science.
Kontras
Management expects long hours from research, very little of the warm and fuzzy attitude projected in other departments makes its way into the labs. The rapid expansion of the company also seems to have outstripped some logistic capacity. One alarming trend is the employment of experienced PhDs as "senior research associates", a position with no apparent career path.